Best breed of dog for working parents?

[Sunkist/Winnie]

Everyone here seems to have quite the range of dog breeds and mixes. From the impression I get a lot of you work during the day so I was wondering what people's opinions were on what type or mix of breeds is best for parent's who have to work during the day (as most of us have to).

My husband and I would like to get a dog, we have a large enough house and yard now to accommodate the two cats plus a dog. But we both work M-F 8-5. We both like the larger breed dogs (ex. labs, rotweillers, bloodhounds, danes) and would prefer one with shorter hair. I have been reading up on different breeds as I see that breed/mix available at the local animal rescue most of them say they shouldn't be left at home during the day alone. But lots of people have to do that now.

I guess it's more of a nature vs. nuture question. If you have a dog, and you bring it up to learn that it is alone for a set amount of time during the day, and you make a point of exercising it well before you go to work, and as soon as you get home from work is that enough to stop it from being lonely and destructive, or does the genetics of the breed still figure greatly in the answer?

We live to remotely so to have someone come in and walk it mid-point during the day is not possible, and daily doggy day care isn't an option.

We'd really like to get a dog, but want to make sure it's the right dog for our situation.

Opinions?