Go Back   Pet forum for dogs cats and humans - Pets.ca > Discussion Groups - mainly cats and dogs > Dog health - Ask members * If your pet is vomiting-bleeding-diarrhea etc. Vet time!

Reply
 
Thread Tools Display Modes
  #1  
Old September 11th, 2009, 03:53 PM
Cinder Cinder is offline
Junior Member
 
Join Date: Sep 2009
Posts: 3
Amer Bulldog & NCL

I have a half American Bulldog half Standard Poodle, would he possibly be able to have Neuronal Ceroid Lipofuscinosis, or would both his parents have to be American Bulldogs in order to possibly have NCL?
Reply With Quote
  #2  
Old September 11th, 2009, 04:15 PM
LavenderRott's Avatar
LavenderRott LavenderRott is offline
Senior Contributor
 
Join Date: Dec 2003
Location: Michigan
Posts: 2,671
Interesting mix!

I am not a genetics expert but I would think that, depending on which breed your dog takes after more, it would be possible.
__________________
Sandi
Reply With Quote
  #3  
Old September 11th, 2009, 04:20 PM
LavenderRott's Avatar
LavenderRott LavenderRott is offline
Senior Contributor
 
Join Date: Dec 2003
Location: Michigan
Posts: 2,671
Here is a link which provides some information for you.

http://www.caninegeneticdiseases.net/CL_site/mainCL.htm
__________________
Sandi
Reply With Quote
  #4  
Old September 11th, 2009, 04:49 PM
Cinder Cinder is offline
Junior Member
 
Join Date: Sep 2009
Posts: 3
Thanks

Thank you, it didn't answer the question if, since it is inherited, would both his parents have to have had the trait, but it is a good source. Thank you.
Reply With Quote
  #5  
Old September 11th, 2009, 05:03 PM
hazelrunpack's Avatar
hazelrunpack hazelrunpack is offline
Moderator
Chopper Challenge Champion, Mini KickUps Champion, Bugz Champion, Snakeman Steve Champion, Shape Game Champion, Mumu Champion, Mouse Race Champion
 
Join Date: Oct 2006
Location: Just east of the Hazelnut Patch, Wisconsin
Posts: 49,746
NCL appears to most often be due to an autosomal recessive. This means that if each parent has one 'bad' copy of the gene and one 'good' copy of the gene they do not show evidence of the disease. However, on average, one quarter of their offspring will inherit two 'bad' copies, and that's when the disease manifests.

It looks like a fairly frequent type of mutation--NCL is found across many breeds and species, and not always from the same mutation. But if both parents have that same recessive 'bad' copy, offspring are at risk to inherit the genes that result in disease.

Has your dog been diagnosed with NCL?
__________________
"We are--each of us--dying; it's how we live in the meantime that makes the difference."

"It's not what you gather, but what you scatter that tells what kind of life you have lived!"

"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Reply With Quote
  #6  
Old September 12th, 2009, 10:15 AM
Cinder Cinder is offline
Junior Member
 
Join Date: Sep 2009
Posts: 3
No, my dog hasn't been diagnosed, I was wondering if he should be, & will talk to the vet, just wanted to get an idea asap. I stumbled upon NCL info by accident & sorry, this will be a long post.

My dog will turn 2 years shortly & he has always been shy/nervous even though I have always socialized him. I got him from a rescue group when he was 5 months old. They said they got him from a breeder who had an accident between an English Bulldog & Standard Poodle. When my dog grew to be very tall and 100 lbs I called the rescue group & asked if the mother really was an English or American Bulldog & they said the mother looked like she was a mix of both (I then saw a picture of her & she does look like a mix of the 2). I then found out that breeders are trying to recreate the Old English Bulldog by mixing English Bulldogs with American Bulldogs, Bull Mastiffs or Mastiffs. I don't care what he is mixed with, I've always had mixed breed dogs growing up but know that English and American Bulldogs have different temperaments & started doing research to help him overcome his nervousness.

I thought I might get a dna test to see what he really is but found out they don't test for American Bulldog and then stumbled on the NCL info & test.

I had recently started to wonder about his eye sight and noticed he's starting to pace. I also started to think he was standing with his back legs spread farther apart but just thought that was part of his growing. Those, and nervousness, are NCL symptoms and his age is right for displaying them. So I am concerned but don't know if it's just coincidence, especially if both parents have to have the trait/gene, if that's the case, since his parents were different breeds (& his mother may be mixed) it wouldn't be possible to have NCL.

I will talk to my vet about this, I just didn't want to worry if it wasn't possible for him to have it.

I do thank all of you for helping.
Reply With Quote
  #7  
Old September 12th, 2009, 12:55 PM
hazelrunpack's Avatar
hazelrunpack hazelrunpack is offline
Moderator
Chopper Challenge Champion, Mini KickUps Champion, Bugz Champion, Snakeman Steve Champion, Shape Game Champion, Mumu Champion, Mouse Race Champion
 
Join Date: Oct 2006
Location: Just east of the Hazelnut Patch, Wisconsin
Posts: 49,746
There is a test available for NCL in bulldogs, as I recall. So if you want to know for sure, you could probably have your vet submit a genetic sample or perhaps you can order a collection kit on your own. I'm not sure how expensive it would be, though.

I'm hoping it's not NCL, though It does appear to be a relatively rare condition!

that all turns out to be wll with your boy!
__________________
"We are--each of us--dying; it's how we live in the meantime that makes the difference."

"It's not what you gather, but what you scatter that tells what kind of life you have lived!"

"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Forum Terms of Use

  • All Bulletin Board Posts are for personal/non-commercial use only.
  • Self-promotion and/or promotion in general is prohibited.
  • Debate is healthy but profane and deliberately rude posts will be deleted.
  • Posters not following the rules will be banned at the Admins' discretion.
  • Read the Full Forum Rules

Forum Details

  • Powered by vBulletin® Version 3.8.7
    Copyright ©2000 - 2014, vBulletin Solutions, Inc.
    vBulletin Optimisation by vB Optimise (Reduced on this page: MySQL 10.00%).
  • All times are GMT -5. The time now is 12:50 AM.