I had a problem with my senior dog's kidney values shooting up after a month on Orijen. It took a few months for them to get back to normal, but they have stayed normal for almost 2 years now and there is no indication of any sort of kidney issue at all. We are pretty certain now that the food was the cause. I've since heard a few similar stories. I still think it's a great food, but it may not be good for all seniors.
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