If all the tests and exams come back showing she is healthy, then it is not something to worry about. Although rare, there are perfectly healthy dogs whose first heat may be delayed to the age of 4 years, and those with a heat interval up to 24 months. You do need the testing to be sure, though. Unbred heats are not beneficial to a dog (except the first one at puberty if the dog is later to be bred), and they increase a dog's chance of developing problems later in life such as pyometra and mammary cancer.
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