Yes I had a Samoyed and I flying from the East coast to the West coast , 3,000 with my dog and I sedated her . The poor dog was so drugged up when we got to California and had trouble walking . When we flew back East for a visit I decided not to sedated and she was OK. I would put thick towel in the dog crate encase he has an accident so pee will not get all over floor on the plane.
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