I just wanted to say that my Great Dane has had a really bad dry, peeling, cracked, bleeding nose for about 3 years.
Everything kept coming back clear at the vet visits and nothing seemed to work.
Yesterday I was told (by a different vet) to try putting Neosporin on his nose (the dog not the vets :-)
Well today after less than one full days application his nose is about 80% improved.
Your experience may vary depending on your dog, his nose and whatever is causing the problem. However I just wanted to share my experience in case anyone else might need help for their friends nose!