Thanks for the replies so far. The in-home care is an interesting idea; we're definitely going to look into that- thanks! We're also going to talk to our vet to see what he recommends. Not being able to take Clifford with us is the one dark spot in this vacation (we're taking the kids to Orlando).
Lise, nymph: if we do go the kennel route, we'll definitely investigate your recommendations as well.