Thanks Hazelrunpack for the advice. Winnie is on 900mg x3 twice a day. And I will be trying milk thistle as well (via... luckypenny and Scottiedog's previous thread) . My friend also suggested Recovery SA for her arthritis...with her enxymes this high, I am afraid I am just trying to make her as comfortable as possible at this point. I guess they can only live as long as they live....