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Convenia®

badger
October 7th, 2008, 12:20 PM
Has anyone heard of this or used it? It's an antibiotic injection which lasts for two weeks. Bird got it the other day for a bladder infection. When I did a little research online, I found that it is normally given for skin conditions, no mention of UI or URI or any of those.
Bird seems better, at least.
Maybe it is an off-label use, which is pretty common.

sugarcatmom
October 7th, 2008, 12:27 PM
I've heard of it, but never used it. It's in the cephalosporin (http://en.wikipedia.org/wiki/Cephalosporin) class of anitbiotics.

Did the vet do a culture & sensitivity on a sterile urine sample?

badger
October 7th, 2008, 01:19 PM
Nothing was cultured. There were clear signs of infection, although no crystals :D. We'll know soon enough if it's the right drug. The prospect of not having to pill him twice a day for two weeks was enough to sway me :laughing:

Now one of the outside cats has some kind of throat infection, he feels very poorly, but will not be pilled. I'm pretty sure he was never vaccinated.

Thanks for the link, sugarcatmom. For a URI, it looks hit or miss to me.

Either which way, it's jackpot month for my vet :frustrated:.

badger
October 7th, 2008, 02:14 PM
Nope. At $50 a pop...

08/09/08
New Antibiotic May Prove to be Convenient for Pets and Their People

Dr. Eric Barchas, DVM
Comments (4)
When I diagnose an infection in a patient, I must prescribe antibiotics. For the person who lives with the pet, that can mean a week or more of giving pills (or a liquid formulation) at home. Under the best circumstances, giving medicine to pets is inconvenient. In the worst cases, it is impossible.

However, a new antibiotic has been approved for use in cats and dogs. It may eliminate the need to give pills at home when pets are diagnosed with certain types of infections.

The antibiotic, called Convenia, was released earlier this year by Pfizer. It is given by injection at the vet’s office. Each injection is effective for up to two weeks. Pets that receive Convenia do not need to take antibiotics at home.

Convenia has two other advantages over conventional antibiotics. First, studies have shown that side effects occur less often with Convenia than with comparable oral antibiotics.

Second, antibiotic-resistant strains of bacteria may be less likely to develop when pets are treated with Convenia. Improper dosing (skipping doses or stopping the medication too soon) is a leading factor in the evolution of antibiotic resistance. Pets that receive Convenia are virtually assured of proper dosing.

So, are vets going to stop stocking other types of antibiotics now that Convenia has hit the market? No. There are two sides to every coin, and I can see a few potential disadvantages to the new medicine.

First, Convenia is not effective against all types of infections. It is labeled for skin infections, wounds and abscesses only.
Also, when a pet develops side effects from oral antibiotics, the medicine can be stopped. Side effects from Convenia are rare. However, if they develop there is no way to discontinue treatment or remove the drug from the pet’s body.

Finally, as a veterinarian I am wary of giving too many injections to cats. This stems from the link between some vaccines and certain types of tumors. Convenia has not been linked to tumors in cats. Nonetheless, I plan to be cautious until the drug has been on the market for a while longer.

AmericanBullMom
October 7th, 2008, 02:57 PM
Hey! I might have to ask my vet about this for Patróns recurring skin infections... You should SEE the battle that ensues in my kitchen every morning to get the horse pill sized antibiotic down his throat!
Thankfully he will USUALLY eat it out of his food, but he has gotten too smart for that too.
I wonder how long it can be used for before becoming ineffective....

RUSTYcat
October 8th, 2008, 11:54 AM
...Convenia is not effective against all types of infections. It is labeled for skin infections, wounds and abscesses only....

badger-

Considering what you've discovered about this drug - and - that you've indicated that no culture was done - and - that it's a bladder infection, if it were my cat, I'd follow up with a culture 4-5 days after the two week period the drug is "good for".......the last thing I'd want is an ongoing infection in that area (and probably moving up into the kidneys).

badger
October 8th, 2008, 12:52 PM
I'd follow up with a culture 4-5 days after the two week period the drug is "good for".

You're right. I'll have to see if my budget can handle it!
I've got three with URI, including the head-snapping sore throat and the vomiting. Plus the kitten I talked about on another thread seems to have been abandoned because he's been living with me full-time for the past week - and he's definitely not vaccinated. He is spending the day outside to reduce his exposure.
So I'm probably taking the one sick cat that can't be pilled to the vet for some kind of intervention (not Convenia) and hoping to cadge treatment for the others without having to pay extra for the exam.
There are a couple of snufflers as well; I am ignoring them.
Bill and Percy are living outside 90% of the time. Like me, they hate crowds.
Whew.

If anyone would like a sweet sweet tuxedo baby, with a bee-bop personality to match, PM me asap.

Gypsymagda
October 28th, 2008, 01:36 AM
Hello,
Anyone experienced any side effects from convenia, like seizures and death? I've had an unfortunate experience, and now find that 3 others have had a similar experience. Anyone know of any problems with convenia in cats?

Nope. At $50 a pop...

08/09/08
New Antibiotic May Prove to be Convenient for Pets and Their People

Dr. Eric Barchas, DVM
Comments (4)
When I diagnose an infection in a patient, I must prescribe antibiotics. For the person who lives with the pet, that can mean a week or more of giving pills (or a liquid formulation) at home. Under the best circumstances, giving medicine to pets is inconvenient. In the worst cases, it is impossible.

However, a new antibiotic has been approved for use in cats and dogs. It may eliminate the need to give pills at home when pets are diagnosed with certain types of infections.

The antibiotic, called Convenia, was released earlier this year by Pfizer. It is given by injection at the vet’s office. Each injection is effective for up to two weeks. Pets that receive Convenia do not need to take antibiotics at home.

Convenia has two other advantages over conventional antibiotics. First, studies have shown that side effects occur less often with Convenia than with comparable oral antibiotics.

Second, antibiotic-resistant strains of bacteria may be less likely to develop when pets are treated with Convenia. Improper dosing (skipping doses or stopping the medication too soon) is a leading factor in the evolution of antibiotic resistance. Pets that receive Convenia are virtually assured of proper dosing.

So, are vets going to stop stocking other types of antibiotics now that Convenia has hit the market? No. There are two sides to every coin, and I can see a few potential disadvantages to the new medicine.

First, Convenia is not effective against all types of infections. It is labeled for skin infections, wounds and abscesses only.
Also, when a pet develops side effects from oral antibiotics, the medicine can be stopped. Side effects from Convenia are rare. However, if they develop there is no way to discontinue treatment or remove the drug from the pet’s body.

Finally, as a veterinarian I am wary of giving too many injections to cats. This stems from the link between some vaccines and certain types of tumors. Convenia has not been linked to tumors in cats. Nonetheless, I plan to be cautious until the drug has been on the market for a while longer.

badger
October 28th, 2008, 03:46 AM
Can I ask you what was the nature of your 'unfortunate experience' with Convenia and what your cat was being treated for?
My own cat seems to have recovered without any problems but I am keeping a close eye on him in case it didn't do the trick.

Gypsymagda
October 29th, 2008, 12:51 AM
yes of course, Booboo was 6 years old. She had been to the vet on Monday and they found a few bad teeth. They gave her the convenia on Monday, kept her until wed morning, giving fluids and food. She was her old. normal self when I picked her up Wed afternoon. The paln was for me to bring her thurs, sat and monday for fluids and a recheck and then deal with the teeth on tuesday morning after the convenia had time to work. Whne I got home wed noght at 11:30, she was seizing on the floor. I d not know for how long. Rushed her to the emergency vet, they gave her 3 courses of increasingly stronger drugs to stop the seizures. Last one was phenol. She satyed the night, I collected her at 8:00 am and took her back to my vet for the full day of monitoring. At 2:00 p.m. she started to have another seizure and my vet gave her half the previous night's dose of pheno.... which stopped the seizure. Doc Lori dropped her back off at the emerg vet Thurs evening without event. I picked her up Firday morning and too her back to Doc Lori for the full day of observation. Still no events but Booboo was still pretty out of it. Sorry this is so long.....
We agreed that I could take her home friday night and watch her, rushing her to the emergency vet if anything happened. We are hoping that she would maybe fight her way back in familiar surroundings. I slept with her on the floor the whole night. She came too several times, took some water with help and actually looked at me. But then at 5:45 a.m. the arching and head shaking started again. She had 2 more by 8:00 a.m. and I took har to lori and had her put to sleep. The very first night this happened I went on line looking for answers. I found a site called Marshfield Clinic and another woman had the same experience. Now since my experience, another person has reported a similar incident. The gentleman on marshfield is a little lacking in his compassion, hence the banter you will see if you visit the site. Anyway, I'm not saying there is anything wrong with the drug. It's just strange that 3 occurences in one month are a bit odd.... yes? Your thought would be much appreciated.

danam314
November 2nd, 2008, 04:00 PM
Hi badger. My dog was given convenia just last week for his skin irritation. We had a bad experience with our old vet just giving our dog meds and not telling us what they were, so our new vet always sits down and explains things to me prior. The first thing my vet told me about it was that they commonly use it to treat bladder infections in both cats and dogs, but it is also effective with skin conditions and irritations. My guess is that it's a safe treatment for your kitty. Of course there are risks with any drug, but she said it was one of the milder, common ones.

I'm sorry about your kitty, Gypsymagda

badger
November 2nd, 2008, 05:33 PM
GypsyMagda, I hope these incidents are being reported back to the drug company (by vets) and are being compiled somewhere, although a handful of cases probably would not carry much weight, even though your poor cat paid the ultimate price. I'm so sorry.

Danam314, I'm very glad to have this information about off-label use for bladder infections. At least it tells me my vet is not a nitwit or worse, reckless :laughing:. Bird has now recovered. How's your dog?

Very poor choice of name, though (they spend millions deciding). Convenient for whom?

hazelrunpack
November 2nd, 2008, 09:10 PM
GypsyMagda, was it MarshfieldClinic or MarshfieldKennel? Marshfield Clinic is near here, but it's a human medical clinic (although they do diagnostic tests for area vets)...but I found a marshfieldkennel link when I queried for 'Convenia'... :confused:

Dr Lee
November 2nd, 2008, 09:54 PM
I just wanted to throw in my :2cents:

I like Rustycat's recommendation of a post treatment culture. Great idea - even if a culture was done. It is important to know that the medication worked and we are not letting a bladder infection sit around when so many can go without symptoms. Also a bladder infection can ascend into a kidney infection.:frustrated:

There was a mention that Convenia was labeled ONLY for certain types of infections. Unfortunately if doctors only prescribed medications for what they were labeled for we would have to work with very little and we would be in a lot of trouble. Cephalosporins work well with UTIs!

Here is some information on the where cephalosporins get concentration into (from Plumb's Veterinary Drug handbook fifth edition)

"Cephalosporins are widely distributed to most tissues and fluids, including bone, pleural fluid, pericardial fluid and synovial fluid. Higher levels are found in inflamed than in normal bone. Very high levels are found in the urine, but they penetrate poorly into prostatic tissue and aqueous humor."

Hope that helps!

Milo's Mum
November 2nd, 2008, 10:14 PM
I took my Persian cat Buddy to our vet on Thursday last week where he was diagnosed with a skin infection on his belly area. He was treated with an injection of Covenia. On Saturday afternoon (48 hours after) I witnessed a 15 - 30 second seizure where he fell off the table to the floor and convulsed.
He was taken to an after hours emergency vet where fortunately he had no more seizures and his blood pathology was normal. I'm interested in gathering information from other pet owners who have had an experience similar.:cat:

badger
November 2nd, 2008, 11:25 PM
Thank you Dr. Lee. Given what people have related here, do you think a definite link can be made with the seizures? Have you seen similar reactions?

danam314
November 4th, 2008, 01:11 PM
Thank you Dr. Lee. Given what people have related here, do you think a definite link can be made with the seizures? Have you seen similar reactions?

I'm curious about this too. I know reactions can always happen, and are usually rare, but is it possible what everyone talks about here can be tied to the Convenia?

And badger: Very poor choice of name, though (they spend millions deciding). Convenient for whom?

You had me laughing so hard. Good point!! :laughing::laughing:

danam314
November 5th, 2008, 03:33 PM
Any further info on this? I went to the vet today and Koda got another shot of Convenia. This is his 2nd shot, 2 weeks apart, and apparently if he needs other antibiotics they will have to be oral, since you can't give more than 2 convenia treatments.

Gypsymagda
November 19th, 2008, 03:51 PM
Hello all,
First let me say thank you for everybody's kind words and the sharing of information. It was what I hoped to gain from the marshfield kennel site (yes that was my oversight), but did not receive. There is now another report posted on that site with the same kind of concerns. I have a hard time now cisiting that site.... if you read the posts there -- for obvious reasons. Yes, my vet did report this to the drug company. They did "make note" which could mean everything -- or nothing. I'm glad lots of folks have had success and that's hopeful. Remember... this drug remains in the system for 2 weeks,,, and residual for a lot longer than that. I'll keep watching for more positive posts...... makes me feel a little better.:candle:

P Barefoot
February 16th, 2009, 07:11 PM
my cat had injection of convenia today and i am concerned that it seems to have affected her sight as the day has gone on.She is craning her head and looking this way and that at things she can see moving which arent.maybe she is hallucinating or seeing double.I am praying it wears of quickly and that nothing worse happens.Has anyone had this experience?

TacoGrl
February 16th, 2009, 10:06 PM
My little man Seth received Convenia for his mouth infection around the end of January and I haven't noticed anything amiss...his mouth 100% better now...of course he had a steriod shot at the same time, so I don't know if it was the combo? Maybe Convenia needs to be "mixed" with something...or perhaps if certain cats have certain levels of certain chemicals or whatnot already in their systems, it may affect how the body reacts to it. We think Seth is around two...maybe age makes a difference? :shrug:

Mommy gets to crate him again at the end of the month to go back to the vet for a follow-up..woohoo :needhug:

badger
March 17th, 2009, 04:34 PM
Poor Wheezy, he had to have a hematoma (accumulation of blood) on the inside of his external ear drained this afternoon. The vet wanted to put him under but because of Wheezy's breathing problems we decided that he would simply drain it right there and hope for the best. Plus antibiotics, eardrops, and more Revolution (because he still has mites). When I said no way was I going to pill this cat since my chances of getting seriously hurt are way too high :laughing:, he immediately offered Convenia. I let him go ahead but reading back in this thread, I am a bit worried. Wheezy won't be going anywhere tonight so I can keep an eye on him. Oh, and I just looked at my bill - are you sitting down? - $46 - bloody hell. I'd like to see some stats on how effective Convenia is, leave aside the side effects.

Wheezer-man was so brave, after we got him out of the cage :p

chico2
March 17th, 2009, 05:48 PM
Imteresting to read about Convenia in case any of my cats should need it.
:fingerscrfor Wheezy Badger:fingerscr

rhartjr
March 17th, 2009, 06:58 PM
Our cat PJ had a shot of Convenia last Wednesday, also had a shot of Depo at the same time. So far so good. My vet only charged $25 though. :fingerscr for Wheezy badger.

Luvbarbaro
April 9th, 2009, 06:28 PM
My cat has UTI problems and also chronic sinus infections. From what I know about this drug, it's a broad spectrum antibiotic. It has helped my Persian cat's sinus problem some, but it's not completely gone and he had the shot one week ago. I think he took Batril once before, but I'll have to get his file out to make sure that wasn't for his UTI. Baytril is excellent for UTI problems though. :) Koko is sick of his runny nose though.:pawprint:

gregoryf
April 14th, 2009, 09:55 PM
Have been taking my cat to the vet for while trying to help with her chronic gum issues. They are pretty bad...He just suggested some injections today (Tues), and I agreed without really asking what they were (not smart). Looked at the invoice when I got home (pretty steep) and saw that she was given convenia, and and an injection of steroids. Not knowing what that was; I looked it up on the internet, and came to this thread. Now i am concerned she may have an adverse reaction. I am going out of town on Sat, and will be keeping a close eye on her until then. Will post any adverse reactions if they occur.

stefanieiris
April 27th, 2009, 08:58 PM
Hi all -- I'm so glad to have found this forum, but a little alarmed about the discussion of seizures in cats. My 17 year old beauty was given a shot of Convenia last night after I took her to the emergency vet for her very bad UTI. She had been given a shot of Batril on Friday afternoon and seemed better, but as the weekend wore on refused the pills (even in cream cheese, half & half, tuna). But today she is so listless and I'm terrified -- she is eating and drinking, which is good, but just not herself at all. I guess it's good news that she's not straining or peeing blood, but I wish I'd see an improvement from the drug. Any sense of how long it takes to make cats feel better? Many thanks!

Molly's_Mommy
May 2nd, 2009, 11:58 AM
:cat: My kitten Molly, is eight months old. I had to take her to the vet two weeks ago because she had a sore and swollen lip. The vet told me it was an ulcer and gave Molly a Convenia injection. She told me it would be better to give her an injection then to try to give her pills for two weeks. I thought it was a great idea. The shot itself was $28.40, total of the vet bill was $111.76. I have an appointment to see the vet again this week since Molly's condition hasn't cleared up and is probably getting worst. :shrug:

sugarcatmom
May 2nd, 2009, 12:13 PM
I have an appointment to see the vet again this week since Molly's condition hasn't cleared up and is probably getting worst. :shrug:

What does Molly eat? Diet can play a role in the development of Rodent Ulcers.
http://www.vet.uga.edu/vpp/clerk/Starnes/index.php

Molly's_Mommy
May 2nd, 2009, 07:52 PM
Molly has been on a diet of Purina kitten chow, ever since she came to live with me(six months ago). It was about a 3-4 weeks ago, I started her on Fancy Feast along with her regular food has a treat. It seems as if her ulcers happened around the same time. I discontinued the Fancy Feast on Monday, when my husband realized maybe shes allergic to the wet food. She also has a lesion on her chin in which it felt like a knob along side of it....I'm very confused about Molly's situation. It seems she has way to much going on. :shrug:

sugarcatmom
May 3rd, 2009, 03:06 PM
Molly has been on a diet of Purina kitten chow, ever since she came to live with me(six months ago). It was about a 3-4 weeks ago, I started her on Fancy Feast along with her regular food has a treat. It seems as if her ulcers happened around the same time.

What flavours of Fancy Feast? There are quite a few ingredients in some of the FF varieties that can be hyperallergenic to cats. Fish is a big one, as are wheat gluten, soy, beef, and "mystery meat" by-products. The Purina Kitten Chow isn't that great either, so my recommendation is to find a grain-free canned food (or else consider a raw diet) with a novel protein source (and no fish). Innova Evo 95% makes venison or duck, and Nature's Variety Instinct also has rabbit, if you can find it. If neither of these are available in your area, maybe Natural Balance Venison or Duck and Green Pea is.

What kind of dishes does Molly eat/drink out of? If they're plastic, that could also be part of the problem. Switching to glass or stainless steel would be better.

Some info for you on why cats should only eat wet food: www.catinfo.org

future_roberts
June 3rd, 2009, 01:57 PM
Two sundays ago, I realized that my 3yr old cat had blood in his urine. Our normal vet wasen't in the office so we had to take him somewhere else. They did a urinalysis and everything else and administered a dose of convenia to him. Well a week went by and there was no improvement. We finally went to our regular vet yesterday and were prescribed 2 oral antibiotics. I was questionalble about this "wonder" 2 week shot. Well I was right it didn't work for his UTI. I thought I would look up this antibiotic shot and saw that it is basically only for wounds and skin irritations, so I'm alittle upset. I hope this antibiotic works for what it is suppose to be used for but I would question if they are trying to give it to treat any urinary infections. I know oral antibiotics are a pain but sometimes it is better treatment for the pet overall.

Stacer
June 3rd, 2009, 05:14 PM
Finn just had her second shot of Convenia last friday. I really wish I had found this thread before we agreed to the first shot. She hasn't had any scary side effects thus far. But she did have an accident outside the litterbox a few days ago, so I may have to go back and request another urinalysis to make sure the Convenia is working. Poor girl.

2catwoman
July 21st, 2009, 11:44 PM
My cat has a bad case of chronic gingivitis. The vet has been treating him with steriod injections every 4 weeks or so, and also a daily does of steriods that are rubbed into his ear. He eats very little, and then stops eating altogether until I take him in for another injection, although last time, he received both the steriod and Convenia injections. So far, so good, no adverse reactions and kitty starting eating in a matter of 3-4 hours vs. 2-3 more days with just the steriod injection. Does anyone have a similar experience and/or know of any other way to treat this condition? The vet is talking about removing some of his molars but doesn't know if it will cure him of the is condition or not. Please share your thoughts with me, any advice? Thanks....

14+kitties
July 21st, 2009, 11:52 PM
2catwoman - welcome. You may get more replies if you started a new thread of your own. Not sure how many would check this thread.

sugarcatmom
July 22nd, 2009, 12:15 AM
My cat has a bad case of chronic gingivitis.

Has the vet mentioned stomatitis at all? It's true that sometimes the only option is to remove all or most of a cat's teeth in order to alleviate the severe pain that a cat with stomatitis experiences. Some things to consider before it gets to that are diet and immune system. What does your cat currently eat? How old is he? Has he been tested for FIV and FeLV?

Here's a link to check out:
http://veterinarynews.dvm360.com/dvm/Medicine/Assessing-treating-refractory-feline-chronic-gingi/ArticleStandard/Article/detail/514808

2catwoman
July 22nd, 2009, 04:27 PM
Thanks for responding...no, my vet has not mentioned stomatitis, but I expect that is what it is. When the problem first erupted, my cat was tested for both FIV and FeLV. In fact, he was tested twice and came up negative both times. This all started right after I adopted him from a local shelter when he was just 10 months old. He is now about 2.5 years old. He eats only hard food. He refuses any canned food, but he will briefly lap at it when I offer it. I feed him Hills brand food, and sometimes I have to mix his diet up with whatever dry food he will go for just to get some nutrients in his system. The vet initially suspected an immune disorder and that has been ruled out since no FIV/FeLV is evident. I've even tried a Venison diet which kitty liked, but still gets the inflammation. We tried the venison thinking that it was potentially a food allergy. Poor thing...he loses weight and once he gets his shot, his weight goes back up some. It is hard to see him starving for days at a time, but the vet warns that frequent injections could result in diabetes. I havel consider putting him to rest, but it is a last resort and only if removing his teeth doesn't help. I hope your kitty is doing ok...

2catwoman
July 22nd, 2009, 04:45 PM
By the way, thanks for the link to the article on stomatitis. I've read up on it before. The article suggests that removal of teeth may be whats in order for my kitty. This is all getting quite expensive, so I'm just hoping that it will all be worthwhile. I am new to this forum, so I am going to have to figure out how to start a new thread so that I can talk to more of the members here. Thanks again for your replies...

RUSTYcat
July 22nd, 2009, 05:00 PM
...I am going to have to figure out how to start a new thread...

If you go to this page (http://www.pets.ca/forum/forumdisplay.php?f=75) (the list of threads in Cat Health), about 1/2 way down on the left there's the "NEW THREAD" button. HTH and welcome!

2catwoman
July 23rd, 2009, 06:22 PM
Tp Rustycat:

Thanks for the link to start the new post! I'm new here and still trying to figure things out. I just posted my issue, so hope to get some responses. Thanks again!!!

BiscuitandGravy
August 20th, 2009, 10:23 AM
You guys should consider yourself lucky, or just smart. My oldest kitty is only 1.5 years old and has never needed antibiotics so I had no idea what kind of a price range was normal. it was SIXTY dollars for the Convenia injection my kitty just got for her very bad UTI. Along with the steroids and office visit grand total was $130. Now I feel gipped after coming on here and hearing others paid half of that. I need kitty insurance.

My cat is pretty hostile and I couldn't imagine getting any pill or liquid in her so I guess it is worth it for that, as long as it works. She just started urinating blood last night so I took her in first thing this morning. The vet didn't recommend a urine culture as I thought he would. He said it was clear from the symptoms it's either a UTI or Lower Urinary Tract disease and with both antibiotics and steroids both would be covered. I sure hope he's right. He said with as small as her bladder is we wouldn't be able to get a culture sample. After doing some research and reading this thread I will be keeping a close eye on her for any adverse effects she may have.

amandabeth
October 2nd, 2009, 10:43 PM
My otherwise healthy 9 year old cat received an injection on Convenia last week for a UTI. He proceeded to go into shock requiring intubation and aggressive resuscitation. He lost his vision, was altered, and his hind legs were paralyzed. He regained his vision and use of his legs about 14 hours later. It broke my heart watching him struggle like that. He spent three days at the vet evaluating all his organ systems to determine what happened. The scant literature demonstrates no adverse reactions, BUT please beware that this may not be a benign medication. Thank god I had a great vet who acted to save his life. I'm sure any antibiotic would have cost less than the $2200 I spent for this reaction.

eculbert
October 20th, 2009, 11:25 AM
My newly adopted old lady cat had it, apparently Normal Saline would have worked better. No problem with her..luckily from what others have said. She had a MDR strain of bug and after I finally got a vet to C/S her, culture and sensitivity test, found out $$$ wasted. Now on a different med, first dose last evening, so no 'report' on it yet.

Why wont vets almost routinely do that test when the 'first' tried med doesn't work? Had to threaten to grab cat and run to lawyer to get them to do that.

Creamsicle'sMom
February 3rd, 2010, 10:48 PM
My cat was given a dose of Convenia last Tuesday for a cold. By last Wednesday night he was mouth breathing and dead by Thursday morning. I've cried for a week and just checked the vet's receipt to learn what exactly he was given. Convenia is for skin infections, not a respiratory infection. I think he went into a severe reaction from it. I read about Convenia's contraindications ans side effects. One of them is anaphylaxis.

I intend to go to the vet and let them get an earful from me. Not only was the cat killed, but I paid them $154 for that. The I paid another $137 to have him cremated thru that same vet's office. Not only have I been ripped off, but he's DEAD and I can't stop crying. And my birthday is tomorrow - as if it can't get more pitiful...I'm using the anger for energy.

garneycat
February 17th, 2010, 12:30 AM
My first post here, hope it gets through.

My old neutered male, about 11-12, is very laid back. He loves being outside in good weather but stays inside when it's cold or raining. He's trained to go to the door when he needs out to use the bathroom and since we do not use a litter box inside, if he has an emergency in the night, he hops in the bathtub.

Our neighborhood has a few feral males that do roam and sometimes my cat encounters one of them. Last Thursday, he was limping just a bit and excessively licking his right foreleg. I took him to the vet and sure enough, there was a puncture wound and the old boy had a fever. It was abcessed.

The vet, whom I like a lot, kept him overnight, lanced the infection and gave him a shot of convenia. I picked him up Friday and he spent the rest of that day plus all day Saturday sleeping. When he did wake up, he was a little shakey on his legs. He did not want to eat or drink but I wasn't concerned too much because we had real bad weather all day, drizzly rain.

On Sunday, he was not any better although the area of surgery was healing very nicely. Old Garney was even more wobbly. Monday I took him back in as he was not urinating or defecating and he could not stand up on all fours. It was as if he could not control his two front legs

He did manage to urinate in the vet's office and the vet was able to do a culture. Blood in the urine. Since Garney already had the convenia in him the vet said it would work for the urinary problem. He also gave him a shot of metacam and sent us home with oral of that same med.

Tuesday, today, Garney's front legs are totally useless, he falls over frontwards when he does try to stand. He's not interested in going to his food bowl but when I took it to him, he did eat some. Same with water. I've been using a syringe which he takes but he cannot raise his head enough to actually eat or drink. He cannot get up enough to move around and he tries to scoot using his back legs but they are very weak too.

I did get a litter box for him and he used it for urine but still has not had a BM. Course, he's not eating more than a couple of tablespoons. Now, tonight, he cannot sit to use the box and I'm afraid he's going to die. It's as if he is paralyzed in the legs. He moves his tail and head.

Could he be having a reaction to the convenia?? Sorry this is so long...I just wanted to get all 6 days in. He was OK except for the abcessed bite wound which was treated, and is still healing really well. Started getting shakey on Saturday. He walked at first like he was a staggering drunk!! Now can't walk at all.

RUSTYcat
February 17th, 2010, 04:03 PM
garneycat- a quick welcome here...but you need to get Garney to a Vet ASAP - those symptoms are very serious and no one here can diagnose what's going on. One of the reactions that's been noticed lately after this drug's use is an onset of anemia - and, that's life-threatening..

If he were my cat, I'd get him to an emergency clinic immediately.

Again, if I were in your position, I wouldn't take him to the same Vet - here's why: there has apparently been much discussion on the Vets' discussion forums over the last several months about severe, adverse reactions to this drug - one would think that any Vet worth his/her weight would, by now, be aware at least of the potential and, if nothing else, at least caution clients to be alert for symptoms.....

My suggestions are either ER or to a feline-only practice - and as quickly as possible.

Remember - this drug is designed to remain in the system for two weeks+.....

Here is a link to a reference to those Vet discussions http://felinediabetes.com/FDMB/viewtopic.php?f=3&t=2107

chico2
February 17th, 2010, 05:32 PM
Garneycat,I am so very sorry for what has happened with your cat,I have learned one thing for sure,my cats will never get injected with Convenia,there seems to be one horror-story after the other.
I :pray:your kitty recovers:pray:

garneycat
February 18th, 2010, 06:49 AM
Rustycat and Chico--thanks to both of you for your kind words.

I must not have been clear in my original post, but Garney was taken back to the vet on Monday, 2-15. That's when the blood in the urine was found.

I made the initial post here on Tuesday night as he was getting worse.

On Wednesday morning, I took him to another vet who did a complete blood workup. It appears he has leukemia, has had it for a long time apparently and the cancer has spread through the blood to his brain.

chico2
February 18th, 2010, 08:57 AM
Oh no,I am so sorry:cry:

RUSTYcat
February 18th, 2010, 03:18 PM
...It appears he has leukemia, has had it for a long time apparently and the cancer has spread through the blood to his brain.

Some clarification is needed here......Feline Leukemia is not a type of feline cancer (Leukemia in humans is considered blood cancer). Feline Leukemia is a bit of a misnomen....it's actually a virus which attacks the immune system and could therefore weaken resistance to cancer occurrence.

I am curious about your reference to Garney's brain......the only way to diagnose a brain tumor is through some form of imaging (x-ray/scan)....was this done? On what basis was any connection to his brain made?

I have no idea whether/not Garney will be able to pull through all this. It would certainly require a skilled, knowledgable and committed Vet (and, perhaps substantial resources).

There is one point I'd like to make, however....many Vets consider a diagnosis of Feline Leukemia (FeLV) as a license to euthanize the cat. The fact is, however, that while FeLV is not curable, it can most often be successfully managed, and is considered a chronic condition (as is diabetes). If you are able and willing to pursue treatment for him, I would strongly urge you to join an online group of other people with FeLV cats - those people's collective knowledge and experience often far outstrips that of most "ordinary" Veterinarians. You will find those people 24/7/365 right here http://pets.groups.yahoo.com/group/FeLVPositiveCats/

There is an excellent site devoted to FeLV right here http://www.felineleukemia.org/ and the owner of that site also runs a support group which can be found here http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

I can well relate to some of what you're going through. Five years ago I lost the love of my life to FeLV (combined with my own total ignorance of Internet resources and an incompetent Veterinarian)...this was a cat who appeared completely healthy and who suddenly collapsed due to the anemia's progression.. I firmly believe, knowing what I do today that, had I availed of the existing resources back then and insisted on a specific course of treatment, he would not have passed before his time.

I hope you'll keep us posted.

purplerain
March 30th, 2010, 12:20 PM
My cat was given a dose of Convenia last Tuesday for a cold. By last Wednesday night he was mouth breathing and dead by Thursday morning. I've cried for a week and just checked the vet's receipt to learn what exactly he was given. Convenia is for skin infections, not a respiratory infection. I think he went into a severe reaction from it. I read about Convenia's contraindications ans side effects. One of them is anaphylaxis.

I intend to go to the vet and let them get an earful from me. Not only was the cat killed, but I paid them $154 for that. The I paid another $137 to have him cremated thru that same vet's office. Not only have I been ripped off, but he's DEAD and I can't stop crying. And my birthday is tomorrow - as if it can't get more pitiful...I'm using the anger for energy.

By the way, I'm in DE and this is from VCA in Glasgow. Watch out.

I' so sorry to hear about your cat. I have a very similar story. My cat was diagnosed with dermatitis. He was given and injection of Convenia and Depo he developed breathing problems and tremors 2 hours after. He seemed comatosed and couldn't eat although he was drinking loads. Took him back to the vet next day and they did a blood test but with the injections in his system it came back inconclusive. Seven days after the Convenia he had to be put to sleep because of an odema and enlarged heart. He was so weak it wa pitiful. The Pathology report also said he was severely anaemic. The anaemia seemed to have developed very quickly because he was not anaemic 2 days before the injections as he was examined by the vet. I suspect Convenia may have contributed to his decline so please be very careful and avoid any injections if at all possible. I have lost a very lovely cat and I have been crying every day for a couple of months now. I'll never be the same again.

chico2
March 30th, 2010, 04:51 PM
Purplerain,I am so very sorry:(what a terrible experience,I will make sure my cats never gets Convenia.

BigBob
April 12th, 2010, 11:38 PM
i took my cat to the vet last thursday because she was showing signs of another UTI. the doctor suggested this awesome sounding alternative to skinned forearms that resulted from a week or two of trying to mash gooey half-digested pills into my poor suffering kitty. he said with one shot, everything would be fixed.
well, the problem was solved. unfortunately i woke up to a lifeless lump laying in the corner of my dining room.

she was otherwise healthy and had a full check up the day before.

take from it what you will, but i doubt i'll choose the "easy way out" next time.

hazelrunpack
April 13th, 2010, 12:52 AM
I'm so sorry for your loss, BigBob :grouphug:

:candle:

chico2
April 13th, 2010, 11:24 AM
OMG,I am so sorry:(
Why is this happening,do the vets not communicate with each other,it is not the first time this happens:frustrated:

purplerain
April 25th, 2010, 05:27 AM
i took my cat to the vet last thursday because she was showing signs of another UTI. the doctor suggested this awesome sounding alternative to skinned forearms that resulted from a week or two of trying to mash gooey half-digested pills into my poor suffering kitty. he said with one shot, everything would be fixed.
well, the problem was solved. unfortunately i woke up to a lifeless lump laying in the corner of my dining room.

she was otherwise healthy and had a full check up the day before.

take from it what you will, but i doubt i'll choose the "easy way out" next time.


I am so very sorry to hear about your cat. If your cat was healthy otherwise then it is suspected the injection could have had an adverse reaction. Have you had a post mortem done? I think you and your vet should report it to the drug company and/or to DEFRA.

tyshalle
May 6th, 2010, 02:21 PM
I am sorry to read these sad stories about covenia. Mine is not so tragic but it breaks my heart anyway. My ten year old male cat, Charley, had a respiratory infection and I took him to the vet in February. The vet told me about covenia, extolled its virtues and said it has no side effects. I told him to go ahead with it. Charley's infection didn't clear up and he started drinking huge amounts of water and losing weight. I took him back to the same vet and he told me Charley was losing weight and drinking water because he had a sore throat. I asked the vet about diabetes and he said Charley didn't have it. Foolishly, I let the vet give Charley another shot. Charley's infection improved but he continued to lose weight and drinking a lot of water. I did everything I could to tempt him to eat, buying him all sorts of wet food, etc. My other pets were happy with the leftovers. I called another vet, who came out to my home to see Charley. His immediate diagnosis was borderline diabetes. He didn't think Charley had leukemia or cancer but he didn't want to take a blood test because Charley's health was so fragile. This vet made a good point. Why give a relatively untried antibiotic when the others work fine? He gave Charley a shot of penicillin and some oral amoxicilin. He recommended starting Charley on low doses of insulin but was willing to try him on glipizide. Charley continues to improve, he is returning to his old self. I truly believe that covenia triggered the diabetes. Like several other people have posted, it takes weeks to get out of the cat's system. Maybe Charley is improving because his body has finally got rid of it all. I hope he comes out of the diabetes. It is possible.

sugarcatmom
May 6th, 2010, 03:51 PM
He recommended starting Charley on low doses of insulin but was willing to try him on glipizide.

Glipizide is actually not a great choice for treating feline diabetes. It further stresses an already stressed pancreas by forcing it to work harder, often burning it out beyond repair. Plus, it can cause liver damage.

I hope he comes out of the diabetes. It is possible.

If Charly truly does have diabetes, a low-carb wet food diet and insulin injections are really the best bet for achieving remission. What does he eat now? How long has he been on glipizide? Do you home-test his blood glucose levels?

purplerain
May 16th, 2010, 05:03 AM
QUOTE=sugarcatmom;915526]Glipizide is actually not a great choice for treating feline diabetes. It further stresses an already stressed pancreas by forcing it to work harder, often burning it out beyond repair. Plus, it can cause liver damage.



If Charly truly does have diabetes, a low-carb wet food diet and insulin injections are really the best bet for achieving remission. What does he eat now? How long has he been on glipizide? Do you home-test his blood glucose levels?[/QUOTE]

RUSTYcat
May 16th, 2010, 02:05 PM
purplerain- you probably believe that your attempt to post today was successful....however, for some reason it appeared as gobbly-gook!

Hopefully this will bring you back to try again!

alexia642
February 27th, 2011, 03:50 PM
My newly adopted old lady cat had it, apparently Normal Saline would have worked better. No problem with her..luckily from what others have said. She had a MDR strain of bug and after I finally got a vet to C/S her, culture and sensitivity test, found out $$$ wasted. Now on a different med, first dose last evening, so no 'report' on it yet.

Why wont vets almost routinely do that test when the 'first' tried med doesn't work? Had to threaten to grab cat and run to lawyer to get them to do that.

So, first in response to this quote, I understand your frustrations as we in the veterinary field typically have the exact same frustration but in reverse. It is so uncommon for us to find owners who are willing to spend the time and money to allow us to send out C/S's that they are frequently not even offered. Most of the time, when we are presenting estimates and an option such as this is on there, I am either a. stared at dumbly, b. told that I am a money grubbing b***h, c. screamed at until I leave the room, d. actually physically assaulted, or e. told that I am insane. It is rare that we get owners with enough stability in their lives to be able to do such options. This is a fault with veterinary medicine in general. We are typically expected to "just know what's wrong" and give the medicine now.

I also am new to this thread of thought about convenia. It is still a fairly new drug in our world, but it is very commonly used (especially in emergency medicine for how many abscesses we see). I have not once seen an adverse reaction to the drug myself, but was confronted with a phone call from a concerned owner the other morning describing the symptoms listed on this forum the other morning. I decided to research myself as none of my other co-workers had any experience with any side-effects of the sort either. I would like to point out that we have to keep in mind that while these side-effects (while quite horrid) may seem common as they are all on here from different people, we must think about the fact that this drug is given to innumerable cats each day who do not have these side-effects. I will, however, continue to look into this matter, as I have cats myself and love them dearly.

RUSTYcat
February 27th, 2011, 05:49 PM
Welcome to the forum, alexia642!

It is so uncommon for us to find owners who are willing to spend the time and money to allow us to send out C/S's that they are frequently not even offered. Quite frankly, I take from this that some of "your" clinic's standards of care are determined by the least caring/educated customers who come through the door...and that just leaves me shaking my head in disbelief.

You've cloaked yourself very generally as "we in the veterinary field".....are you a Veterinarian/Technician/other?

While you may not have received reports from your clients of serious side effects associated with Convenia, my understanding is that such reports/discussions exist - some on VIN - and I am aware of others in open discussion boards/forums. I give you one example http://www.felinediabetes.com/phorum5/read.php?8,1964921

Without the benefit of any veterinary education, even I can recognize from the generally available literature that this is NOT a drug to be given willy-nilly (as appears to be the general practice now) (and quite obviously peddled as such by the manufacturer - read the name of it again!)...the "official" info from the maker listed on drugs.com states "Warnings: To limit the development of antimicrobial resistance, the extra-label drug use of cefovecin is not recommended http://www.drugs.com/vet/convenia-injectable-lyophile-can.html From the UK's National Office of Animal Health: "It is prudent to reserve third generation cephalosporins for the treatment of clinical conditions, which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials or first generation cephalosporins. Use of the product should be based on susceptibility testing..." http://www.noahcompendium.co.uk/Pfizer_Limited/Convenia_80_mg_ml_powder_and_solvent_for_solution_ for_injection_for_dogs_and_cats/-43050.html

Finally, inconveniently burried in the manufacturer's data sheet is this FOREIGN MARKET EXPERIENCE: The following adverse events were reported voluntarily during post-approval use of the product in dogs and cats in foreign markets:
death, tremors/ataxia, seizures, anaphylaxis, acute pulmonary edema, facial edema, injection site reactions (alopecia, scabs, necrosis, and erythema), hemolytic anemia, salivation, pruritus, lethargy, vomiting, diarrhea, and inappetance. http://www.pfizerah.com/PAHimages/compliance_pdfs/Convenia_Full_Infill_041108.pdf Only in "foreign markets", huh? Not bloody likely!

chico2
February 28th, 2011, 08:52 AM
Thank's Rusty,I think we all need to be informed,to be able to make the right choice for our cats and question any treatments we are unsure of.

ancientgirl
February 28th, 2011, 10:49 AM
The last time I took Oksana in for a UTI the vet gave her this. She's so incredibly hard to pill and even giving her liquid oral medication gets hard after a day or two, as I wind up chasing her until I grab her and she winds up spitting out most of it. She's not had an incident since last November :fingerscr and I've never seen any adverse reaction from the medication in her.

RUSTYcat
February 28th, 2011, 03:17 PM
I knew that Dr. Lisa Pierson (catinfo.org) frequently rails against the indiscriminate use of Convenia - today I noticed that she now has a page dedicated to Convenia on her website - it's easy reading and can be found here http://www.catinfo.org/convenia.php

catnmouse
March 2nd, 2011, 08:37 PM
I'll throw in my two-cents worth regarding my experience with Convenia. I have a 16 year old, hyperthyroid cat named Rupert with a chronic sinus infection that's been ongoing for the past 18 months. A sinus culture suggested nasal lymphosarcoma but all these months later it has shown no sign of progressing so my vet suspects it's quite likely a deep seated bacterial infection lodged well inside the sinus cavity and perhaps not cancer after all. It responds well to antibiotics but, till recently, symptoms would re-occur once the antibiotics wore off.

Before the cancer diagnosis, I had struggled to give Rupert oral antibiotics for several rounds (we know how hard it is to get that horrible liquid pink stuff into a squirming cat). Once we had the cancer diagnosis from the lab (it was vague; it said the culture "indicated a condition consistent with nasal lymphosarcoma"), the vet suggested Convenia to keep Rupert comfortable, thinking it would be only a matter of time till the cancer progressed. So for more than a year, Rupert received an injection of Convenia every 6 weeks. It seemed to be a wonderful treatment for keeping his symptoms under control -- after each injection he would have 4 or 5 symptom-free weeks and then the sneezing and discharge would start again, and soon after that he'd get lethargic and miserable, so we'd go back for another shot. However, as of this moment, he hasn't had an injection for 8 weeks and there are no signs of symptoms flaring up, so I'm crossing my fingers!

I know there are all kinds of reasons why long-term treatment with antibiotics isn't ideal. Initially, because we thought he had cancer, it seemed like a good way to help keep him comfortable. As time wore on, my fear was that he would develop a resistance to the antibiotics. I guess only time will tell as to whether the problem is permanently gone, but Convenia offered us a way to keep Rupert's quality of life high without the trauma of oral antibiotics.

Koteburo
January 22nd, 2013, 12:04 AM
I'm so glad it worked for your dog. What a relief must be for you that not only he didn't have an adverse reaction but it was good for him as well.
Scully had it once and she never had any side effects from it either, sadly that's not always the case.
But good thing Dodger is fine.

grandmahodie
January 22nd, 2013, 12:07 AM
Hi all, I just wanted to say something positive about the Convenia injection that my 60 LB dog received on Saturday.
Dodger was diagnosed with IBD ( inflammatory bowel disease) 1 year ago, we have finally managed to control his episodes with diet and a daily low dose of Prednisone. With IBD in some dogs comes a skin infection called Pyoderma (took me forever to find out what these sores were) because their immune system is compromised, Oral antibiotics are out of the question for him as it will cause a flair up of the IBD going through his intestinal tract. Last Saturday I took Dodger to the Vet because he has skin sores on the trunk of his body that the topical ointment weren't helping, so I asked my vet about this Convenia injection...WHAT A GOD SEND THIS STUFF IS to my dog..I watched him carefully for the first 48 hours, and to my amazement, his stools are nice and solid still and the sores are healing and no longer red and irritating him..Yes the injection was pricy ( for a dog his size it was about $200) but well worth every penny, the antibiotic injection stays in their system for 2 weeks. It hasn't upset his system whats so ever, which makes both my husband and I are very happy and the dog is even happier

Twocents
December 7th, 2013, 11:09 PM
People whose pets have suffered adverse reactions or death and called the drug manufacturer are reporting that the company is telling them there have been NO reactions. Info is on the FB page "Convenia adverse reactions in cats/felines and dogs/canines"

Disciplinary hearings for vets who have given this drug for extra/off-lable uses have been disciplined. One vet association said that Convenia should not be given without obtaining the clients "informed consent".
.................................................. ................................................ Whatever "informed consent" means (are they going to tell you that the drug ay kill your pet if there's an adverse reaction because it can't be removed from your pet? .................................................. .................................................. ............. I'm concerned about ANY injectable antibiotics being given to pets. Did you know they don't normally give intramuscular antibiotics to people anymore because it's too painful? Even when giving antibiotics via an intravenous (IV), the rate has to be slow so it doesn't cause discomfort to the patient. (This info is from my mother, a nurse, who has also received IV antibiotics.)

Due to risks outlined by Dr. Lisa Pierson and adverse reactions and deaths of pets posted here and elsewhere online, it's extremely unlikely that a long-acting drug like Convenia would EVER be approved for use in people, so why should pet owners be putting their animals at unnecessary risk?

Dr. Pierson's info on Convenia - http://www.catinfo.org/?link=convenia

Article on ConsciousCat.net (can subscribe to comments as comments are still being made there) - http://consciouscat.net/2011/09/26/convenia-for-cats-sacrificing-safety-for-convenience/