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Toxoplasmosis!!!

Constance67
June 26th, 2008, 10:18 AM
Finally! A diagnosis for Beaver... he's got toxoplasmosis and will start treatment today. :thumbs up


In case no one remembers what was going on with him, here's the link to the thread about his symptoms...

http://www.pets.ca/forum/showthread.php?t=53424


Thanks for all the help and support I was given on this.

Radha
June 26th, 2008, 10:35 AM
That's great Constance - all good wishes. I hope he's better really soon! My kitty's called Sandy - he's 10 and I can empathise with how panicked you would have felt. Take care!:pray:

hazelrunpack
June 26th, 2008, 09:01 PM
I'm glad you finally got a diagnosis! :highfive:

How long will he be on meds?

Constance67
June 26th, 2008, 11:00 PM
I'm not sure. He gave us 2 weeks worth of pills to begin with. He goes in for a check up next Thursday to see how things are going and then we'll take it from there.

The weird thing is, he wasn't intentionally testing for this, it just was a test included in a panel for Feline Leukemia, FIP and FIV. So I think we got really lucky, as well as being lucky in the fact that he's been on antibiotics for 3 weeks already. They weren't as strong as what he's taking as of today, but maybe that's what kept him from getting even worse.

The sickest he got was last Saturday when his fever was up to almost 105. That's when he was started on Clavamox, which seemed to make him almost 100% back to normal, except for his eyesight. We're hoping it will improve as well. :fingerscr

growler~GateKeeper
June 27th, 2008, 01:23 AM
Toxo didn't occur to me :shrug: Good thing you've now got a solid diagnosis & treatment plan to clear this all up :thumbs up

:fingerscr :goodvibes: for more improvement soon

Love4himies
June 27th, 2008, 06:10 AM
I am so glad you finally got a diagnosis! :thumbs up Your kitty should be fine in no time with treatment.

Constance67
June 29th, 2008, 11:03 PM
He seems to be a lot worse. He's been on the meds since Friday and it's like he's going down hill. All he does is lay around and he seems to have lost more weight. I'm calling the doctor tomorrow.

Does anyone know anything about toxoplasmosis? I've googled it and read a lot about it, but not much about treating it in cats and how they respond to the treatment.

I'm just so tired of seeing him not feeling well and I feel so guilty because I can't help him anymore than I've done already. :sad:

growler~GateKeeper
June 29th, 2008, 11:24 PM
This article has some info on the infection in cats:
http://www.vet.cornell.edu/fhc/brochures/toxo.html

It seems like most cases of Toxo infection in cats don't show or have very mild symptoms

Definately try to get him in tomorrow, he may need a change in dosage or switch to another med

:goodvibes: keep us updated

rainbow
June 29th, 2008, 11:41 PM
Here is another website....

http://www.peteducation.com/article.cfm?articleid=770

Sending lots of good luck for Beaver. :fingerscr :goodvibes: :fingerscr :goodvibes:

hazelrunpack
June 29th, 2008, 11:45 PM
I hope he's better soon, Constance :fingerscr :goodvibes:

TeriM
June 30th, 2008, 01:17 AM
Sending some healing vibes your way :goodvibes::goodvibes::goodvibes:.

sugarcatmom
June 30th, 2008, 06:43 AM
He seems to be a lot worse. He's been on the meds since Friday and it's like he's going down hill. All he does is lay around and he seems to have lost more weight. I'm calling the doctor tomorrow.


What are the meds that he's on? Is he still on Clavamox? Antibiotics quite commonly give cats digestive issues so I'm wondering if that could be part of the issue. Definitely talk to the vet about it.

14+kitties
June 30th, 2008, 08:55 AM
:goodvibes::fingerscr for better health soon.

Constance67
June 30th, 2008, 11:47 AM
Thanks everyone. I'm waiting for the doctor to call me back now.

He's an indoor cat, has been for about 6 years now.

He's on Clindamycin now. He did really really well on the Clavamox, too bad it wasn't the one to fix the toxo.

sugarcatmom
June 30th, 2008, 12:56 PM
He's on Clindamycin now. He did really really well on the Clavamox, too bad it wasn't the one to fix the toxo.

Is it liquid Clindamycin or capsules? It can also cause problems (my cat got horrible diarrhea from the liquid). If your giving capsules, it's extremely important that you follow it with a chaser of liquid or a food treat or else it can get stuck in the cat's throat, causing Erosive Esophagitis. More here: http://www.catinfo.org/pillingcats.htm

Good luck. Let us know what the vet says.

Constance67
June 30th, 2008, 06:30 PM
It's in capsule form. I put a little butter on it to make it slippery before giving it to him and then I give him snacks to eat afterward as well as his water. He took the first couple easily in some pill pocket snacks, but then on the 3rd one, he bit the pill and now he's not as easily fooled. Which is where the butter came into the picture.

He called me and had me take his temperature. It was 104 so he then told me to go ahead and give him clavamox as well as the clindamycin, but at staggered intervals instead of both at the same time.

Said to take his temperature again in the morning and to let him know how he's doing.

He vomited just a little bit a little while ago, the poor little guy. This is getting so hard to handle, I just hate seeing him feel so bad and there's nothing I can do to fix it.

I'm beginning to wonder if I should take him to another doctor, but I hate to start the process all over again with more blood tests and more waiting on the tests to come back.

I'm just to the point that everytime I see him feeling so bad I get upset with him and that doesn neither one of us any good at all. :sad:

sugarcatmom
June 30th, 2008, 07:56 PM
How is his appetite? Is he eating normally? Make sure you give the Clavamox with food, either mixed in or after he eats, it will be easier on his stomach. You may want to think about adding some probiotics as well since his intestinal flora is getting walloped by the antibiotics. Keep a close eye on his appetite. If he goes without eating for more than a day, call the vet.

Constance67
June 30th, 2008, 10:43 PM
He hasn't been eating much at all since he's been on the clindamycin, but he eats some. Since giving him the clavamox earlier tonight, he seemed to be a bit more interested in food, but not nearly like he would normally eat. But at least he's eating some... right?

It's like the clavamox makes him feel better and back to his old self, at least that's what it did the last time he was on it. I hope it works again this time, so we'll see in the morning if there's any change.

I can't thank you all enough for your help, even if it's just words of encouragement. Not everyone understands how important a pet can be and I'm really glad I found this place. Thank you all so much for just being here.

Constance67
July 1st, 2008, 06:50 AM
Well I have 10 minutes til kill before I can go meet the doctor at the office. Had to call in for an emergency visit because Beaver is doing so badly. He was too weak to come out from behind the dresser this morning. I had to reach in and get him and he just felt so small and frail. All he could do was barely stand and make really sad sounds.

I told God to either make him better or to just go ahead and take him... :sad:

Love4himies
July 1st, 2008, 08:34 AM
Oh no, I am so sorry to hear your kitty is not doing well, I was hoping with the diagnosis he would make a quick recovery.

Constance67
July 1st, 2008, 09:25 AM
He had a fever again, 104. He gave him some fluids to hydrate him and a shot to bring the fever down. He's now on Clavamox and Albon 5%. My husband and I have decided if he doesn't improve with this within a couple of days, that it's time for us to say goodbye. We just can't put him through much more of this. It's too sad to see him wasting away to nothing and suffering through it all like he has been in the last few days. It's not an easy decision at all, it was made through many tears from the both of us but we just feel like it's the right thing to do.

Hopefully it won't come to that though. :fingerscr :pray:

Love4himies
July 1st, 2008, 01:33 PM
http://www.petplace.com/drug-library/clindamycin-antirobe/page1.aspx

I found a link about this drug. Is the vet sure it is toxoplasmosis?

hazelrunpack
July 1st, 2008, 02:31 PM
I'm sorry you and Beaver are having such a difficult time, Constance :grouphug:

:goodvibes: for a quick turnaround and a complete recovery !

growler~GateKeeper
July 1st, 2008, 02:56 PM
Is the vet sure it is toxoplasmosis?

Unfortunately often when cats are really sick w/Toxo there is an underlying case of FIP or FIV that causes the severe symptoms. Has Beaver been tested for either? There is an Elisa Snap Test they can do in clinic.

:goodvibes: :goodvibes:

Constance67
July 2nd, 2008, 08:18 AM
They did what they called a four panel test for Feline Leukemia, FIP, FIV, and Toxo.

Yesterday, about 5 hours after his first dose of Clavamox, he's up and walking around, eating food and drinking water as well as asking for snacks. It's just amazing the difference that Clavamox makes in him. This morning he's still doing pretty well and was up and ready for breakfast. He's by no means what I'd call "well", but he's not so weak that he can't stand up either.

He hates the Albon and acts like it makes him gag, luckily there's only 3 more days of that for him to go through.

I just wish we could figure out what's going on with the Clindamycin and why it messes him up so badly. I've been consulting with several Veterinarians, one in Arizona where my sister in law works and a couple here in Arkansas who specialize in cats. They're all confused with this as well. I'm getting copies of his blood work today to email to my sister in law so they can have a look at it. I'm beginning to wonder if it's actually Toxo that he really has.

hazelrunpack
July 2nd, 2008, 08:31 AM
Clindamycin is a pretty harsh drug in our experience. None of the dogs seem to tolerate it very well and I can't take it for more than a few days, either. Do you think he may just be allergic to it?

:fingerscr that whatever he has can be totally cleared up with the Clavamox! It may not be the drug of choice, but it seems to be helping him!

:goodvibes: for continued improvement!

Love4himies
July 2nd, 2008, 08:51 AM
Unfortunately often when cats are really sick w/Toxo there is an underlying case of FIP or FIV that causes the severe symptoms. Has Beaver been tested for either? There is an Elisa Snap Test they can do in clinic.

:goodvibes: :goodvibes:

That's what I thought too, cats who show signs of this have a compromised immunity system to begin with.

There was a sentence in the Cornell University link that stated if the clindamycin doesn't work within a couple of days that the diagnosis of Toxoplasmosis should be questioned.

:grouphug: to you constance67, I hope your kitty gets better soon.

Dr Lee
July 2nd, 2008, 09:38 AM
IThe weird thing is, he wasn't intentionally testing for this, it just was a test included in a panel for Feline Leukemia, FIP and FIV.

Constance,
:sorry: it took so long for me to respond. I have been unavailable lately and will not be able to read many posts for a while.

If he was not intentionally looking for toxo, it may be that his gut feeling was right and that toxo is an incidental finding. Love4himies is correct, with clindamycin, for most cases the effects should be rather quick. However there are some cases which do not respond quickly. If toxo is the cause, then the prognosis can be worse if response is not seen. Toxo can lead to permanent neurologic damange in some cases. Overall clindamycin is a great medication, I use it commonly. In cats, though, many can get some GI upset. If clindamycin was solving the other clinical signs, then I often suggest adding in pepcid and/or an antiemetic such as metoclopramide.

It sounds like his clinical signs are responsive to Clavamox which means that there is a bacterial infection which is sensitive to Clavamox. Perhaps a longer course of treatment would be beneficial (4-6 weeks?)

If clinical signs recur, then further diagnostics to evaluate for an underlying disease with secondary bacterial infections would be in order. It would be helpful to find the location of the bacteria, however in a cat this can be easier than it sounds.

From what you have stated, I don't know that you need to change vets. It sounds like he is running all of the tests. When we come up with a positive test result, it is natural and correct to pursue treatment in that direction until there is enough evidence (such as lack of clinical response to the clindamycin and positive response to Clavamox) to re-evaluate. It sounds like we have a fever of unknown origin (FUO) case. These can be difficult, especially in cats. The infection can be in so many locations and some difficult to diagnose.

I am sorry if I am not much help on this one. Toxoplasmosis can be difficult and can be present for a long while prior to clinical signs. I think a lot of this will depend upon how sure we are that toxo is the cause. If you are looking for a second opinion, perhaps ask your veterinarian if he thinks an internal medicine specialist is in order. This would be better than getting 'another cook in the kitchen'. An internal medicine specialists job is to handle the unusual cases and make sure that the patient is headed in the correct path. Then they hand the case back to your regular, more affordable, veterinarian. :pawprint:

Constance67
July 3rd, 2008, 10:18 AM
That's ok Dr. Lee, I understand you have a busy life on this board as well as off this board, but any help you give is always much appreciated.

He's doing a bit better this morning, woke us up by scratching on the bedroom door because he wanted us to get up and give him some treats. They just are addicted to those Temptation treats! So I got up and gave him a few of those and check him out. His eyes haven't improved back to the stage they had improved to. I think the doctor was wrong when he told us to stop using the drops after he diagnosed him with Toxo, so I've started using the drops again.

We take him to an internal medicine specialist today and are hoping he'll be able to tell us what's going on and if it's all bad news or if we should keep trying and having hopes that he can come through this. If he has anymore bad days like he did Tuesday morning, then he'll be making the decision for us. It's just too hard to see him so sick.

But anyway, I'm thinking positive today! His appointment is at 5:30 this evening and it's about 60 miles away, but it's definitely worth it... he's definitely worth it. I've gotten copies of all his tests to take with me too.

I'll update this later tonight and let yall know what the doctor says. :fingerscr :pray:

hazelrunpack
July 3rd, 2008, 01:07 PM
Please do keep us posted, Constance! :grouphug:

:goodvibes: and :fingerscr for good results tonight!!!!

Love4himies
July 3rd, 2008, 01:20 PM
I hope you get some answers :fingerscr

Please don't give up too easily on him. There is a member on this board named Swaysbodyguard, it is a touching story of a man who loves his dog so much and never gave up on her even when some of us thought there was no hope.

http://www.pets.ca/forum/showthread.php?t=42910

rainbow
July 3rd, 2008, 01:54 PM
My thoughts and prayers are with you, Constance. :grouphug: :pray:

Sending lots of good wishes for Beaver. :fingerscr :goodvibes: :fingerscr :goodvibes:

Constance67
July 3rd, 2008, 08:41 PM
Thanks again everyone for all the well wishes and :fingerscr 's that you've given us.

The visit to the doctor went ok. I took all his paper work with me and it seems he has a few indicators saying he may have FIP, but he said that it's not certain that he does. He believes he's definitely got Toxo, but it said it was odd for him to not respond to the Clindamycin.

He had a fever of 104.6 so they gave him some fluids to bring that down and added some Vitamin B to the fluids to give him a boost. During the drive home would could tell a difference in him already. He demanded to be let out of the carrier, so we did and he rode in the back glass of the car watching the trees go by. He seemed to really enjoy the ride and was having a good time, so my husband and myself both agreed that if things don't keep taking a turn for the better, that at least we know we did all we could and he had an adventure today that he seemed to enjoy.

The doctor was really nice to him, treated him like a little person and even talked to him more than he talked to us... which we really liked.

Anyway, we decided to start him up again on the Clindamycin but this time we're starting with a smaller dose of only 25mg three times a day in stead of 75mg twice a day. He said he may have had a bad reaction last time to the Clindamycin because he may have had a fever and we didn't realize it. So we're gonna check his temp now and then and if he developes a fever we'll be giving him a baby aspirin, but only once a week for that. So if it continues we'll see about getting him some fluids to bring it down. But, if he takes a bad turn for the worse again, we're gonna have to let him go. We've talked about it and feel good about it because we just had to say goodbye to one of our others almost 2 years ago and we know he'll be there waiting to take care of Beaver.

Ok, I gotta stop talkin about it before I upset myself. :)


Again, thanks to you all for everything and now that we basically have Beaver's situation settled, I'm hoping to check out a little more of your board here and get to know you all a bit better.

hazelrunpack
July 3rd, 2008, 10:17 PM
I'm glad he seemed to enjoy his outing. :fingerscr that the lower dose of Clindamycin works for Beaver.

:grouphug:

growler~GateKeeper
July 4th, 2008, 12:42 AM
:fingerscr :goodvibes: the lower dose works well for Beaver

Riding out free in the back of the car is what my girl prefers as well, so I'm glad to hear that improvement in Beaver already - he was active in his surroundings :thumbs up

:grouphug: :goodvibes:

rainbow
July 4th, 2008, 12:59 AM
I hope the reduced dose of Clindamycin works for Beaver as well. :fingerscr :goodvibes:

Magicwildwolf69
July 4th, 2008, 08:48 AM
i hope the lower dose works as well. Hope things work. You'll be in my prayers.

Constance67
July 6th, 2008, 02:54 PM
He's gone. :sad: :sad: :sad: :sad: :sad: :sad: :sad: :sad:

sugarcatmom
July 6th, 2008, 03:57 PM
Oh no!! I'm so sorry. :rip: little Beaver. :candle::candle:

rainbow
July 6th, 2008, 04:13 PM
Constance, I am so sorry to hear about Beaver. :sad: My deepest condolences to you for your loss. :grouphug:

:rip: Beaver :candle:

hazelrunpack
July 6th, 2008, 09:38 PM
I'm so sorry for your loss, Constance. You're in my thoughts during this difficult time. :grouphug:

:candle: Beaver

growler~GateKeeper
July 7th, 2008, 11:35 PM
Constance :sad: I'm so sorry :2huggers:

:rip: sweet :angel2: Beaver :candle:

Please know Beaver is running free and healthy at The Rainbow Bridge (http://www.indigo.org/rainbowbridge_ver2.html) with all those who went before him :grouphug:

Constance67
July 11th, 2008, 02:29 PM
Thanks everyone for all the well wishes and :candle: 's.

Sorry my post about him being gone was so brief, but at the time it was all I could manage. Today I can finally give a little more information about how he left us.

Saturday he started having seizures, which were very short, only lasting a few seconds, but they were still seizures. Afterwards he'd be very scared and would need to be calmed down and his health was in a steady decline. So Saturday we stopped the Clindamycin and only gave him his Clavamox to help him rest well through the night since it has seemed to make him feel a bit better. Then we decided to make the call Sunday morning to our doc and let him go.

Sunday morning I woke him up and he was ready to have something eat, but he never really managed to eat much. I gave him all the juice from one can of Fancy Feast, which he only managed to eat about half of, but he enjoyed it and that was what mattered.

We paged the doctor and waited for him to call us back. Around an hour later, about 9am, he called and said he could meet us in 25 minutes. Of course that's when my husband and myself realized this was it, it was really time to say goodbye to our little man. Needless to say, the tears started up for the beginning of what would be a very long day.

I had this blue fleece type shirt that I wore every winter, one that Beaver just absolutely loved! Whenever I put it on, he'd be on me like a magnet fluffing it up, purring and almost sucking on it. So I dug that out and wrapped him in it. Time it was around his little body I could hear a very faint purr, something he hadn't done in at least a week or so. We got a box and his sweater and headed to the doctors office with him wrapped in my blue shirt and in my arms.

We got to the office and went inside where we talked to him, hugged him and told him what a wonderful guy he is and how much we love him. Then it was over and he was gone. Finally not having to fight for each day that came along. We put him in the box, still wrapped in my blue shirt and stuck his little sweater in there with him. His sweater was something he didn't really like, but he tolerated for us because we thought he looked so cute in it. He was just easy going like that and would do anything for us. We never left it on him long, just a few minutes when I would take him outside so it was easier to hold onto him and not enable him to slide out of his halter. :)

Anyway, after it was over, we drove to my parents house out in the country where he was buried beneath some big trees in a clearing by a swing. My Mom is going to plant some pretty flowering bushes around him and we're going to get a big rock to put out there to mark his place. It's somewhere we'll know his at, somewhere for us to go visit and just a great place for him because he really loved his "Granny and Grandpa", just as he was loved by them.

We went home afterward and yea, more tears were flowing throughout the day. We weren't crying because of what we had to do, we knew and know it was the right thing. The doctor said seizures was a sign it had moved to his brain. We were crying because we missed the little guy and it just didn't feel right with him not being here with us. He's just everywhere we look, he was so much a part of our lives. With us both working from home, we saw him all the time and everywhere, it will be quite awhile before we're used to him not being around.

His best buddy, ButterBean, the orange and white one in my avatar pic with Beaver, is missing him as well. But we spend a lot of time with him so he doesn't go into a depression. I think one good thing about Beaver being sick for awhile instead of just being gone suddenly, was the fact that ButterBean got a chance to get used to him not being around to play with and hang out with him as he always had. He seems to be doing ok, though he does get in my lap a bit more than he did when Beaver was around.

So it's over now, he doesn't have to fight any longer. He was so brave throughout it all though, fighting hard and putting up with so many needles and doctors and drugs. He's finally himself again.

I'd like to post some pictures of him if anyone is interested.

And again, thanks for all the help, support and words of encouragement and understanding from each and everyone of you. Yall are the best. :grouphug:

hazelrunpack
July 11th, 2008, 02:38 PM
We'd love to see some pictures of Beaver, Constance! :grouphug: And some of his buddy, ButterBean, too.

Maybe start a thread in the photo forum or in the remembrance forum for pets that have passed to the Bridge?

I'm so glad you came back. I hope things have gotten a little easier for you since your last visit. :grouphug:

rainbow
July 11th, 2008, 02:42 PM
Yes, I agree, we'd love to see some pics. I think a tribute in the rainbow bridge forum would be a good idea.

growler~GateKeeper
July 12th, 2008, 01:41 AM
:grouphug::grouphug::grouphug:

Love4himies
July 13th, 2008, 07:41 AM
I am so sorry he didn't recover. :grouphug: Would love to see pictures of him.